铁和自在癌症中的交叉体
Xiaodi Lv1,2, Bin Wang3, Ming Dong4
1Department of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Autoimmunity
|December 9, 2023
概括
这份对2012-2022年铁和自研究的文献分析揭示了关键趋势和有影响力的出版物. 研究结果为调节细胞死亡机制和潜在的癌症治疗策略提供了洞察力.
科学领域:
- 细胞生物学 细胞生物学
- 生物化学 生物化学
- 在瘤学瘤学.
背景情况:
- 了解铁和自之间的相互作用对于推进癌症治疗至关重要.
- 研究旨在澄清这些受调的细胞死亡途径之间的交叉通话,以开发治疗方法.
- 确定新的生物标志物和未来的研究热点在铁和自是关键目标.
研究的目的:
- 分析了2012年至2022年间发表的关于铁和自研究的文献统计数据.
- 绘制研究格局的地图,识别关键贡献者,并了解这个领域的演变.
- 为开发有效的药理机制和用于癌症治疗的新生物标志物提供见解.
主要方法:
- 使用Web of Science核心集合 (WOSCC) 数据库进行图书统计分析.
- 从2012年1月1日到2022年9月1日收集的数据.
- 使用CiteSpace 6.1.R2和VOS viewer 6.1.8软件进行分析,绘制网络结构并识别关键节点.
主要成果:
- 由55个国家的980个组织的4183名作者共发表了756篇文章.
- 中国,美国和德国在出版物方面处于领先地位.
- 关键词包括自,细胞死亡和氧化应激,对铁和喘的研究得到了高度引用.
结论:
- 这项研究提供了关于铁亡和自死交叉通话的研究的全面概述.
- 这些发现揭示了适应性应激反应和调节细胞死亡的基础分子机制.
- 结果支持开发新的治疗点和癌症治疗的信号监管网络.
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