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相关概念视频

Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

2.1K
Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
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Overview of Electron Microscopy01:25

Overview of Electron Microscopy

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The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.
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Ultrathin liquid cells for microsecond time-resolved cryo-EM.

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相关实验视频

Updated: Jul 9, 2025

Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy
10:29

Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy

Published on: February 5, 2017

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用时间分辨率电子显微镜可视化纳米级动力学.

Jonathan M Voss1, Pavel K Olshin2, Marcel Drabbels3

  • 1Ecole Polytechnique Fédérale de Lausanne (EPFL), Laboratory of Molecular Nanodynamics, CH-1015 Lausanne, Switzerland. jonathan.voss@epfl.ch.

Chimia
|December 9, 2023
PubMed
概括
此摘要是机器生成的。

科学家们正在开发先进的时间分辨率电子显微镜技术,以在原子分辨率下观察复杂的纳米级相互作用. 这项研究旨在捕捉材料科学和化学中的超高速动态.

关键词:
在位置电子显微镜.在现场的电子显微镜.纳米颗粒 纳米颗粒纳米规模的动力学蛋白质 蛋白质 蛋白质时间分辨率电子显微镜.

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All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics
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All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

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Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy
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Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy

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相关实验视频

Last Updated: Jul 9, 2025

Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy
10:29

Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy

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All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics
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All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

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Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy
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Visualizing Diffusional Dynamics of Gold Nanorods on Cell Membrane using Single Nanoparticle Darkfield Microscopy

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科学领域:

  • 材料科学 材料科学 材料科学
  • 物理 物理学 物理
  • 化学 化学 化学

背景情况:

  • 纳米级系统表现出复杂的行为,由于众多的相互作用.
  • 观察这些现象需要原子分辨率和高时间精度.
  • 将观察时间尺度与系统动态相匹配对于理解至关重要.

研究的目的:

  • 介绍一下专注于先进显微镜的实验室活动概述.
  • 突出新方法和仪器的发展.
  • 为了实现纳米级动态的高速,原子分辨率的观测.

主要方法:

  • 使用时间分辨率电子显微镜作为主要技术.
  • 开发新的方法来提高时间和空间分辨率.
  • 专注于用于高速数据采集的仪器仪表的进步.

主要成果:

  • 关于先进电子显微镜正在进行的研究的概述.
  • 在开发纳米级观测新技术方面取得的进展.
  • 展示捕捉超快原子动态的能力.

结论:

  • 时间分辨率电子显微镜对于理解复杂的纳米系统至关重要.
  • 方法和仪器的持续开发是关键.
  • 该实验室正在推动超高速原子分辨率成像领域的发展.