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Updated: Aug 14, 2026

A Simple Benchtop Filtration Method to Isolate Small Extracellular Vesicles from Human Mesenchymal Stem Cells
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隔离方法对介质干细胞衍生的细胞外囊泡的特征和功能活性的影响

Ricardo Malvicini1, Giada De Lazzari2, Anna Maria Tolomeo3

  • 1Laboratorio de Regulación Génica y Células Madre, Instituto de Medicina Traslacional, Trasplante y Bioingeniería, Universidad Favaloro-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina; Department of Women's and Children's Health, University of Padua, Padua, Italy; Laboratory of Extracellular Vesicles as Therapeutic Tools, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy; LIFELAB Program, Consorzio per la Ricerca Sanitaria, Padua, Italy.

Cytotherapy
|December 9, 2023
PubMed
概括

与超过 (UF) 相比,离子交换色谱 (IEX) 给出了更多的RNA和蛋白质,以及与超过 (UF) 相比,对介质细胞流体细胞衍生的细胞外囊泡 (MSC-EVs) 产生了更大的免疫调节效应. 对于临床级MSC-EV生产,IEX可能会优于IEX.

关键词:
细胞外囊泡中的细胞外囊泡.离子交换色谱学 离子交换色谱学隔离隔离隔离隔离隔离介质细胞层细胞.超过是一种超过.

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