在异质多孔介质中,对以定数感应驱动的生物膜分散进行孔尺度反应运输建模研究
1Department of Geological Sciences, Chungnam National University, Daejeon 34134, South Korea.
Mathematical biosciences
|December 9, 2023
概括
微生物定数感应 (QS) 控制生物膜在多孔介质中的分散. 孔隙结构和流动动力学,以及生长和分散率,决定了QS信号和生物膜振荡.
科学领域:
- 微生物学 微生物学
- 生物物理学的生物物理.
- 环境工程 环境工程
背景情况:
- 微生物利用定数感应 (QS) 进行集体决策,调节昂贵的表型.
- 生物膜的形成和分散是受到环境因素影响的关键过程.
研究的目的:
- 在异质多孔介质中研究生物膜生长和QS控制的分散.
- 了解孔隙结构,流速和生长/分散速率对QS动态的影响.
主要方法:
- 采用一个孔尺度反应式运输建模方法.
- 模拟了各种流体流动条件和生物膜生长场景.
主要成果:
- 质量学过程取决于生物质密度,孔隙结构,流速和生长/分散率.
- 孔隙架构启动QS;向导导致振荡式生物膜生长.
- 振荡被促进高QS信号度的因素抑制 (例如,快速增长,缓慢分散).
结论:
- 在复杂的环境中建立了QS控制的生物膜动态的数学框架.
- 孔尺度建模提供了对微生物集体行为和生物膜管理的基本见解.
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