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Updated: Jul 9, 2025

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
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暴露于挥发性有机化合物会引起心血管毒性,这可能涉及DNA甲基化

Zhuoyan Li1, Jieru Lu2, Xuehua Ruan1

  • 1Department of Pediatric Cardiology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Toxicology
|December 9, 2023
PubMed
概括

母亲暴露于挥发性有机化合物 (VOC) 可能会损害胚胎心血管发育. 这项对斑马鱼胚胎的研究揭示了VOC诱导心脏异常,可能是通过影响关键基因的DNA甲基化变化.

关键词:
心血管有毒性心血管毒性通过DNA甲基化.环境污染物 环境污染物心脏的发展心脏的发育挥发性有机化合物 挥发性有机化合物

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