在非洲人群中执行6个查对阻断性睡眠呼吸暂停症的分数
A P Wachinou1,2,3, A A Fiogbe2, T Totah3
1Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Benin.
West African journal of medicine
|December 10, 2023
概括
在非洲人群中,NoSAS8查工具显示了中度至重度阻塞性睡眠呼吸暂停 (OSA) 的最高积极预测值. 这使得它成为在资源有限的环境中进行OSA查的合适选择.
科学领域:
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
- 诊断工具 诊断工具 诊断工具
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 诊断在低收入国家具有挑战性,因为睡眠记录的获取有限.
- 查工具对于识别可能受益于进一步OSA评估的个人至关重要.
研究的目的:
- 为了评估六个OSA查得分的表现与非洲人口的客观睡眠记录 (呼吸道伪造) 相比.
- 在资源有限的环境中确定最有效的OSA选工具.
主要方法:
- 贝宁睡眠与社会 (BeSAS) 研究包括1810名参与者,这些参与者接受了呼吸道多重扫描 (PG) 并完成了OSA查问卷 (STOP,STOP-Bang,柏林,NOSAS [≥8和≥5],无呼吸暂停,GOAL).
- 根据PG数据的呼吸暂停-呼吸暂停指数 (AHI),对OSA严重程度进行了分类.
- 性能指标包括ROC曲线下的面积,灵敏度,特异性和正预测值 (PPV) 在查得分中进行了比较.
主要成果:
- 对于中度至严重的OSA,GOAL和无呼吸暂停显示了ROC曲线 (0.70) 下的最高面积,其次是NoSAS5 (0.69).
- NoSAS5表现出最高的灵敏度 (0.73),而NoSAS8实现了最高的特异性 (0.91).
- 所有得分都有较低的正预测值 (PPV),NoSAS8具有最高的 (0.38).
结论:
- 这项研究是第一个在非洲人口中比较OSA查得分的研究.
- 在资源有限的环境中,NoSAS8被推作为OSA的首选查方法,因为它具有最高的,尽管低的PPV.
- 可能需要进一步的研究来改善不同人群中查工具的PPV.
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