关节全关节置换的生存率:一个系统的审查和元分析
Felipe Gomes Gonçalves Peres Lima1, Larissa Gonçalves Cunha Rios1, Luiz Renato Paranhos2
1Post-Graduate Program in Dentistry, Dental School, Federal University of Uberlândia, Uberlândia, Brazil.
Journal of oral rehabilitation
|December 10, 2023
概括
整体关节 (TMJ) 假肢显示了97%的高生存率,大多数故障是由于感染而发生的. 然而,证据确定性非常低,突出显示了关节置换研究中的潜在偏见.
科学领域:
- 口腔和牙面部外科手术
- 生物材料科学 生物材料科学
- 重建性手术是一种重建性手术.
背景情况:
- 总关节置换用于复杂的关节 (TMJ) 疾病.
- 关节假肢的长期生存和失败模式尚未得到充分证实.
研究的目的:
- 为了确定全关节 (TMJ) 假肢的生存率.
- 为了确定TMJ假肢失败的主要原因.
主要方法:
- 在八个数据库中进行系统的电子文献搜索,截至2023年3月.
- 包括前性研究,对全关节假肢进行至少12个月的随访.
- 使用GRADE方法对生存比例的元分析和证据确定性的评估.
主要成果:
- 分析了6项涉及320名患者的前性研究.
- 整体关节假肢的总生存率为97% (95% CI:95%;99%).
- 假肢失效,主要是由于感染,通常发生在手术后6个月内.
结论:
- 整体TMJ假肢似乎是一种安全的手术,存活率很高.
- 目前的证据基础以非常低的确定性和显著的偏差来源为特征.
- 需要进一步进行高质量的前性研究,以证实TMJ全关节置换的安全性和有效性.
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