一种短TR单回声旋转回声喘息方法,用于评估肝脏T2
Marshall S Sussman1, Kartik S Jhaveri2
1Joint Department of Medical Imaging, University Health Network, Mount Sinai Hospital, and Women's College Hospital, University of Toronto, 585 University Avenue, Room NUW-1-141D, Toronto, ON, M5G 2N2, Canada. marshall.sussman@utoronto.ca.
Magma (New York, N.Y.)
|December 10, 2023
概括
一种新的,快速的旋回回声T2映射技术允许呼吸屏住肝脏铁量化. 这种方法提供了准确的T2测量,克服了传统更长的扫描时间的局限性.
科学领域:
- 磁共振成像是一种磁共振成像技术.
- 医学物理 医学物理
- 放射学 放射学是一门学科.
背景情况:
- 传统的单回声旋回声T2映射用于肝脏铁量化需要很长的扫描时间,超过典型的喘息持续时间.
- 这种局限性阻碍了临床环境中的准确评估,特别是对于铁过载患者.
研究的目的:
- 为了研究一种新的,加速的单回声旋回声T2映射技术,适用于喘息获取.
- 为了评估这个短TR (~100毫秒) T2映射方法的准确性和可靠性,用于肝脏铁量化.
主要方法:
- 开发了一个短TR (~100毫秒) 单回声旋回声T2映射序列,在~17秒内获取每个回声时间 (TE) 图像.
- 为了减轻T1偏差,重复时间 (TR) 随着每次TE的增加而增加,保持恒定的TR-TE间隔.
- 用幻影,9名健康志愿者和5名1.5T铁过载患者进行了验证,将结果与传统方法和Ferriscan.com进行了比较.
主要成果:
- 在幻影中,恒定TR-TE技术产生了公正的T2估计,与传统的恒定TR方法不同,该方法低估了T2.
- 健康的志愿者在恒定TR-TE T2值和参考T2值之间没有显著差异.
- 在铁过载患者中,在恒定的TR-TE T2值和Ferriscan之间观察到很高的相关性 (r2 = 0.95),差异很小 (0.6 ± 1.4 ms).
结论:
- 开发的短TR单回声屏息旋回声T2映射技术提供了公正的T2估计.
- 这种加速方法在幽灵和临床肝脏应用中对肝脏铁的量化是准确和可靠的.
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