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Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
在乳腺癌幸存者的长期患者报告的手臂症状
Alison Laws1,2,3, Mirelle Lagendijk4, Samantha Grossmith1
1Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
三分之一的乳腺癌幸存者报告了长期的手臂症状,其中较高的比例与下淋巴结解剖和某些乳腺重建类型有关. 严重的症状并不常见,但手臂病情在幸存者护理期间需要注意.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 癌症的生存率 癌症的生存率
背景情况:
- 乳腺癌的生存率显著提高.
- 长期的手臂症状是幸存者的担忧.
- 了解与治疗相关的发病率对于生活质量至关重要.
研究的目的:
- 评估乳腺癌幸存者的长期手臂症状的患病率和严重程度.
- 为了确定地方区域治疗和手臂症状严重程度之间的关联.
- 为了告知幸存者护理和患者咨询.
主要方法:
- 在2002年至2012年期间对1126名乳腺癌患者 (阶段0-III) 进行的横截面研究.
- 患者报告的手臂症状使用EORTC QLQ-BR23问卷进行评估.
- 线性回归用于分析治疗与手臂症状 (AS) 评分之间的关联.
主要成果:
- 882名患者填写了问卷;平均随访时间为10.5年.
- 64.3%的人报告没有手臂症状;9.3%的人报告严重症状.
- 骨淋巴结解剖 (ALND) 和自主乳房重建与更高的AS分数有关.
结论:
- 大约三分之一的乳腺癌幸存者经历了治疗后10年的手臂症状.
- 臂部发病率受到关和乳房外科手术程序的影响.
- 幸存者护理应解决因治疗而产生的潜在的手臂相关问题.
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