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孕产妇和产周因素对新生儿心电图的影响
Caroline Boye Thygesen1, Maria Munk Pærregaard2, Julie Molin2
1Department of Cardiology, Herlev-Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark, caroline.boye.thygesen@regionh.dk.
Neonatology
|December 10, 2023
概括
母亲和围产因素累积影响新生儿心电图,导致QRS轴向左移动和延长QT间隔. 这些效应虽然在正常范围内,但突出显示了心脏过渡过程.
科学领域:
- 新生儿心脏病学 新生儿心脏病学
- 产周医学 产周医学
- 心血管生理学心血管生理学
背景情况:
- 新生儿心肌发育在出生时仍在进行,使心肌细胞易受母体和周围影响.
- 了解这些影响对于新生儿心脏健康评估至关重要.
研究的目的:
- 研究母亲和围产因素对新生儿心电图 (ECG) 参数的影响.
- 评估这些因素对新生儿心脏电活动的累积影响.
主要方法:
- 对15928名新生儿 (0-30天) 进行前性队列研究,心声图正常.
- 分析母亲/人口统计数据,怀孕和出生因素与心电图参数之间的关联.
- 将新生儿按孕产妇/产后因素数量 (0至≥5) 分组为组,以比较心电图结果.
主要成果:
- 在新生儿心电图上观察到孕产妇/产周因素的累积影响.
- 在QRS轴的显著向左移动和QT间隔延长被发现具有增加因子.
- 极端组 (0与≥5因子相比) 显示QRS轴左移4.3%多,QTcF延长0.8%,最明显的是在生命的第一个星期.
结论:
- 母亲和围产因素累积影响新生儿心电图参数.
- 结果表明QRS轴向左移动,QT持续时间增加,保持在正常参考范围内.
- 这项研究增强了对新生儿心脏过渡和孕产妇/孕产后因素对心脏的影响的理解.
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