多变量曲线分辨率-交替最小平方 (MCR-ALS) 在药物分析中的当前应用:综述

Mohammed Alaoui Mansouri1, Mourad Kharbach2, Abdelaziz Bouklouze3

  • 1Nano and Molecular Systems Research Unit, University of Oulu, FI-90014 Oulu, Finland; University of Liege (ULiege), CIRM, Vibra-Santé HUB, Laboratory of Pharmaceutical Analytical Chemistry, CHU, B36, B-4000, Liege, Belgium.

PubMed
概括

多变量曲线分辨率-交替最小平方 (MCR-ALS) 为分析药品数据提供了一种强大的方法. 本综述详细介绍了MCR-ALS在药物溶解,稳定性,多态性和量化方面的应用.

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MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
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