生活微生物的饮食摄入量与成年人慢性便秘之间的关联
Chuanli Yang1, Qin Hong2, Teng Wu3
1Key Laboratory of Environmental Medical Engineering and Education Ministry, School of Public Health, Southeast University, Nanjing, Jiangsu, China; Department of Preventive Medicine, School of Public Health, Southeast University, Nanjing, China; Department of General Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
更高的饮食活微生物摄入量可能会降低慢性便秘 (CC) 的风险. 这项研究发现,食用活微生物和CC患病率之间存在反向关联,这表明潜在的肠道健康益处.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
- 微生物组研究 微生物组研究
- 公共卫生 营养 公共卫生 营养
背景情况:
- 慢性便秘 (CC) 是一种普遍存在的胃肠道疾病,具有重大公共卫生影响.
- 饮食中的活微生物在CC病因学和管理中的特定作用仍然不完全理解.
- 现有的研究还没有明确地确定食用活微生物的消费与肠道规律性之间的联系.
研究的目的:
- 调查饮食中的活微生物摄入量与大量成年人群中慢性便秘 (CC) 的患病率之间的关联.
- 为了确定更高的食用活微生物的消费是否与较低的患CC的可能性相关.
- 用国家健康和营养调查数据分析这种关系.
主要方法:
- 利用来自国家健康和营养检查调查 (2005-2010) 的11,170名成年人的数据.
- 根据布里斯托尔便形状尺度和评估的饮食活微生物摄入量 (低,中,高) 定义的CC.
- 采用多变量回归模型,根据人口,生活方式和健康因素进行调整,以分析相关性.
主要成果:
- 在研究人群中,CC的年龄调整后患病率为7.06%.
- 在更高的饮食活微生物消费和CC (OR:0.77,95%CI:0.61,0.97) 之间观察到一个显著的反向关联.
- 在控制多个潜在混因素之后,这种关联仍然很重要,这表明了强大的关系.
结论:
- 研究结果表明,饮食中活微生物的摄入量增加可能与慢性便秘的风险降低有关.
- 这项研究强调了活微生物在促进肠道健康和缓解便秘方面的潜在作用.
- 建议进行进一步的前性研究,以验证这些发现,并探索这种关联背后的机制.
更多相关视频
03:50Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
Published on: August 18, 2023
07:15An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Drugs for Treatment of Constipation-Predominant IBS
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Bacterial Flora of the Large Intestine
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
Anatomy of the Intestines
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
