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Updated: Jul 8, 2025

Production of a SARS-CoV-2 Virus-Like-Particle System to Investigate Viral Life Cycles In Vitro
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来自SARS-CoV-2 S1,S2,RBD和N重组蛋白的自组合的粉样样纳米结构

Olga V Morozova1, Valentin A Manuvera2, Nikolay A Barinov3

  • 1Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 1a Malaya Pirogovskaya Street, 119435, Moscow, Russian Federation; Ivanovsky Institute of Virology of the National Research Center of Epidemiology and Microbiology of N.F. Gamaleya of the Russian Ministry of Health, 16 Gamaleya Street, 123098, Moscow, Russian Federation; Moscow Institute of Physics and Technology, 9 Institutsky Per., 141700, Dolgoprudny, Moscow Region, Russian Federation; Sirius University of Science and Technology, Olimpiyskiy ave. b.1, township Sirius, Krasnodar region, 354340, Russian Federation.

Archives of biochemistry and biophysics
|December 10, 2023
PubMed
概括

来自SARS-CoV-2蛋白质的自组装纳米颗粒自发形成粉样结构,可能导致蛋白质病变并影响疫苗的稳定性. 这些纳米结构表现出稳定性和受体介导的细胞进入.

关键词:
光蛋白纳米颗粒的ACE-2受体介导的内细胞结合.粉样蛋白是什么 粉样蛋白是什么生物材料是一种生物材料.克隆,就是克隆人类.冠状病毒复合蛋白片段的重组蛋白片段.电子显微镜 (EM) 是一种电子显微镜.纳米技术纳米技术蛋白质自我组装的过程蛋白质病变是一种蛋白质病变.自组装的固体蛋白质纳米粒子.

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