相关实验视频

Updated: Jul 8, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
11:53

Substrate Generation for Endonucleases of CRISPR/Cas Systems

Published on: September 8, 2012

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在Cas4-缺少Crispr系统中解开外源DNA处理:探索了一种新型绕道途径

Xinming Su1,2, Xiaoyu Jin1,2, Zehua Wang1,2

  • 1Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, 310000, China.

Advanced biology
|December 10, 2023
PubMed
概括

集群定期间隔的短平行体重复 (CRISPR) 系统使用适应性免疫的替代途径. 一个新的模型揭示了DnaQ样外核酶 (DEDDh) 在Cas4缺陷的CRISPR系统中如何处理DNA.

关键词:
在CRISPR/Cas系统中.在Cas1-Cas2复合体中.这就是Cas4的原因.类似DnaQ的外核酶.适应性免疫是一种适应性免疫.外源的DNA处理.

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