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Updated: Jul 8, 2025

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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肺癌和双重向药物治疗中的HIF-1α和EZH2之间的相互作用

Jianmin Wang1,2, Cheng Yang1,2, Huashen Xu3

  • 1School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, 110016, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|December 10, 2023
PubMed
概括

这项研究揭示了增强体同源2 (EZH2) 的增强剂在肺癌中介于对低氧诱导因子 (HIF-1) 抑制剂的抵抗. 一种新型化合物,DYB-03,针对HIF-1和EZH2,显示出组合疗法的前景.

关键词:
在 EZH2 中使用.这就是HIF-1α.双重目标药物 双重目标药物反法规反法规的规定.肺癌是一种肺癌.

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