用布托芬醇诱导麻醉对术后恶心和吐的影响:一项随机对照试验
Fang Xie1, De-Feng Sun2, Lin Yang3
1Department of Anesthesiology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China.
World journal of clinical cases
|December 11, 2023
概括
在老年患者的胃肠道 laparoscopic 手术后 24 小时内,butorphanol 有效地减少术后恶心和吐 (PONV). 这种阿片类止痛药还提高了在麻醉后护理单位 (PACU) 的患者舒适度.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
- 胃肠病学 胃肠病学
背景情况:
- 手术后恶心和吐 (PONV) 是常见的并发症,影响胃肠道腹腔镜手术后老年患者的康复.
- 管理PONV对于改善患者的治疗结果和健康状况至关重要.
研究的目的:
- 评估与sufentanil相比,butorphanol在接受胃肠道腹腔镜手术的老年患者中预防PONV的疗效.
- 评估醇对患者舒适度和其他康复参数的影响.
主要方法:
- 一项随机对照试验,涉及110名接受胃肠道腹腔镜手术的老年患者 (≥65岁).
- 患者在麻醉诱导期间接受了布托尔法诺 (40μg/kg) 或苏芬坦尼尔 (0.3μg/kg).
- 测量结果包括PONV发病率,麻醉剂剂量,患者舒适度得分和第一次浮气的时间.
主要成果:
- 与sufentanil (23.64%与5.45%相比) 相比,在手术后24小时内,丁香醇显著降低了PONV发病率.
- 对于其他临床特征,包括48小时PONV发病率,两组之间没有发现显著差异.
- 接受布托尔法醇治疗的患者在麻醉后护理单位 (PACU) 报告了更高的舒适度.
结论:
- 布托尔法作为一个有效的替代 sufentanil 麻醉诱导在接受胃肠道腹腔镜手术的老年患者.
- 丁醇在减少早期PONV和改善麻醉后护理单位舒适度方面具有显著的益处.
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