手术方法是否会影响服用克洛皮多格雷尔的关节骨折患者的出血?
Enver Kılıç1, Olgun Bingöl1, Guzelali Ozdemir1
1Orthopaedics and Traumatology, Ankara Bilkent City Hospital, Ankara, TUR.
Cureus
|December 11, 2023
概括
在接受关节部骨折关节整形手术的 klopidogrel 患者中,无论是后部还是前侧外科手术方法都不会显著影响出血. 外科医生可以根据经验和患者需求选择技术.
科学领域:
- 整形外科手术 整形外科手术
- 老年医学 老年医学
- 心血管药理学心血管药理学
背景情况:
- 腿部部骨折在老年患者中很常见,通常需要进行半关节整形.
- 腿部部骨折的患者可能正在服用克洛皮多格雷尔,一种抗血小板药物,增加出血风险.
- 对于这些患者来说,手术方法的选择是关于出血并发症的辩论.
研究的目的:
- 为了比较后部和前侧外科手术方法之间的出血结果,用于克洛皮多格雷尔治疗的患有股骨骨折的患者的手术整形.
- 评估手术方法对输血需求,血液损失和住院时间的影响.
主要方法:
- 一项对61名60岁以上的患者进行的比较研究,这些患者在服用克洛皮多格雷尔时因股骨部骨折而接受了副关节整形手术.
- 患者被分为两组:后部接近 (组1) 和前侧接近 (组2).
- 评估的参数包括血红蛋白水平,输血需求,红细胞 (RBC) 损失,手术持续时间和住院时间.
主要成果:
- 在红细胞损失方面,在后部和前侧组之间没有发现显著差异 (p=0.37).
- 手术持续时间和住院时间在两种手术方法之间也没有显著差异 (分别为p=0.41和p=0.37).
- 两组患者的人口统计和并发症都相似,确保了可比的基线特征.
结论:
- 在后部和前侧外科手术方法之间的选择不会显著地影响皮多格雷尔治疗的患者进行骨部骨折的脑关节整形手术的出血.
- 外科医生应根据其个人专业知识和患者的具体要求选择手术方法.
- 这一发现支持为这种患者群体选择手术技术的灵活性.
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