在活体中进行烧伤痕评估,采用斑点折叠关系和联合光谱和时间域光学连贯性断层扫描
Qiang Wang1, Peijun Gong2,3,4, Hadi Afsharan1,3
1The University of Western Australia, Optical+Biomedical Engineering Laboratory, Department of Electrical, Electronic and Computer Engineering, Perth, Western Australia, Australia.
Journal of biomedical optics
|December 11, 2023
概括
光学连贯断层扫描 (OCT) 和OCT血管造影 (OCTA) 可以评估烧伤痕的血管性. 这些成像技术揭示了痕和健康皮肤之间血管密度和流动速度的明显差异,有助于评估烧伤痕.
科学领域:
- 生物医学工程 生物医学工程
- 皮肤病学 皮肤病学
- 医疗成像医学成像
背景情况:
- 烧伤后的痕和缩在烧伤管理中带来了重大挑战.
- 准确的伤口愈合评估对于预防烧伤并发症至关重要.
- 烧伤痕血管性的非侵入性评估为愈合提供了洞察力.
研究的目的:
- 调查OCT和OCTA在烧伤痕血管信息方面的能力.
- 评估使用OCT/OCTA数据进行烧伤痕评估的可行性.
主要方法:
- 在9名烧伤患者中利用了OCT和OCT血管学 (OCTA).
- 从健康的皮肤和相邻的痕组织获得的数据.
- 采用斑点图形关系,多普勒OCT和联合光谱/时间域OCT进行分析.
主要成果:
- 与健康的皮肤相比,烧伤痕的血管分布显著不同.
- 烧伤痕中的血管密度比健康组织高67%.
- 烧伤痕血管的轴流速比健康组织快25%.
结论:
- 海外和东欧国家和地区是评估烧伤痕的可行工具.
- 这些技术可以根据血管结构区分痕和健康组织.
- 证明了评估烧伤痕严重程度和进展的实用性.
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