儿童意外铁中毒 - - 一个教学机构的经验
Jolly Chandran1, R Sanketh1, Siva Vyasam1
1Department of PICU, Christian Medical College, Vellore, Tamil Nadu, India.
Journal of family medicine and primary care
|December 11, 2023
概括
儿童的意外铁中毒是一个严重的风险,由于母亲过量服用铁片,往往是致命的. 安全储存和家长咨询对于预防严重后果和儿童死亡率至关重要.
科学领域:
- 儿科毒理学 儿科毒理学
- 临床儿科 临床儿科
- 公共卫生 公共卫生
背景情况:
- 急性铁毒性是一种危及儿童生命的疾病,是由于母体铁片意外过量服用导致的.
- 关于儿童群体中铁中毒的具体情况和结果的文献有限.
- 这项研究通过介绍儿童意外摄入铁的病例系列来解决数据的稀缺性.
研究的目的:
- 调查意外铁中毒的儿童的临床形状和结果.
- 确定与儿科铁毒性病例死亡率相关的风险因素.
- 强调预防措施和父母教育关于铁补充剂安全性的重要性.
主要方法:
- 从2009年1月到2019年12月,在南印度的一家儿科重症监护室 (PICU) 进行了一项回顾性研究.
- 纳入标准包括所有患有意外铁毒的儿童.
- 数据分析的重点是临床表现,管理和患者的结果.
主要成果:
- 五名儿童意外摄入铁片,平均年龄为25.8个月.
- 两名儿童患有突发性肝衰竭,并因这种疾病而死亡,尽管在一个案例中接受了包括血合成在内的支持性护理.
- 虽然大多数儿童 (3/5) 经过胃洗,脱胺和全肠灌治疗后活着出院,但死亡率与凝血病,急性肝衰竭和延迟呈现有关.
结论:
- 儿童意外铁中毒是严重的公共卫生问题,死亡率很高.
- 有效的管理涉及及及时的医疗干预,包括胃洗,desferrioxamine,和潜在的等离子酶.
- 初级保健医生必须向家长提供铁片的安全存储建议,以防止意外摄入并减少儿童死亡率.
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