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Updated: Jul 8, 2025

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
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Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

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同进化与分子动力学模拟相结合,为集成体复合体子单元之间的相互作用提供了结构和机制的洞察力

Bernard Fongang1,2,3,4, Yannick N Wadop1,4, Yingjie Zhu5,4

  • 1Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.

Computational and structural biotechnology journal
|December 11, 2023
PubMed
概括

这项研究引入了修改后的直接合分析 (DCA) 与分子动力学 (MD) 模拟相结合,以预测蛋白质复杂结构. 这种方法成功地揭示了具有挑战性的蛋白质复合体的结构细节,有助于结构生物学研究.

关键词:
在CPSF100中使用.在CPSF73中使用.DCA DCA 的意思是什么?高斯的卷积是高斯的卷积.在INTS11中,我们可以使用INTS11.在INTS4中使用.在INTS9中使用.分子动力学分子动力学剩余的共同演变

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