在前列腺癌治疗时常被忽视的性副作用的患病率和预测因素:一个横截面的观察性研究
Sami Beji1, Alexander Bjørneboe Nolsøe1,2, Christian Fuglesang S Jensen1
1Department of Urology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, 2730, Denmark.
Sexual medicine
|December 11, 2023
概括
针对前列腺癌的低剂量率支臂治疗 (LDR-B) 可以导致高潮功能障碍和阴茎变化. 患者应该被告知这些常见的性副作用,而性活动期间尿失禁是罕见的.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 性医学性医学性医学性医学
背景情况:
- 低剂量率支臂治疗 (LDR-B) 是局部性前列腺癌的标准治疗方法.
- 勃起功能的结果得到了充分的证据,但其他性功能变化没有得到充分的研究.
研究的目的:
- 为了调查高潮功能障碍,性活动期间的尿失禁 (UIS),阴茎形态变化和LDR-B后的阴茎感觉障碍.
- 确定这些潜在副作用的预测因素.
主要方法:
- 在2010年至2020年期间,对178名用LDR-B治疗的患者进行了横截面问卷研究.
- 评估的国际勃起功能指数-勃起功能域 (IIEF-EF),高潮,UIS,阴茎形态和感官障碍.
主要成果:
- 80%的患者性活跃;70.8%的患者经历了勃起功能障碍 (ED).
- 常见的副作用包括高潮强度下降 (46.9%),高潮时间增加 (49.3%),高潮相关疼痛 (18.3%),阴茎长度减小 (25.2%).
- 勃起障碍是改变性高潮感知,性高潮疼痛和阴茎缩短的重要危险因素.
结论:
- 在前列腺癌的LDR-B治疗后,高潮功能障碍,阴茎形态变化和感觉障碍是常见的.
- 在性活动期间尿失禁 (UIS) 影响少数患者.
- 告知患者这些副作用并对其进行监测至关重要.
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