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血液图参数与对比诱导脏病的发展之间的关联在患者呈现非ST升高心肌梗塞

Esra Dönmez¹, Sevgi Özcan¹, İrfan Şahin¹

¹Department of Cardiology, Bağcılar Training and Research Hospital, Bağcılar, İstanbul, Türkiye.

Advances in laboratory medicine

|December 11, 2023

概括

平均血小板体积 (MPV) 和中性粒细胞/淋巴细胞比率 (NLr) 可以预测非ST段升高心肌梗塞 (非STEMI) 患者的对比诱导性脏病 (CIN),这些患者正在接受皮肤穿冠状动脉干预 (PCI). 这些血液学标志物与传统的风险因素相结合,为CIN风险评估提供了一个有希望的方法.

科学领域:

心脏病学心脏病学
腎臟病學 (nephrology) 是一種醫學專業.
血液学血液学血液学

背景情况:

像MPV和NLr这样的血液图参数是心血管疾病中已知的炎症指标.
对比诱导性脏病 (CIN) 是皮肤穿透冠状动脉干预 (PCI) 后的一个显著并发症.

研究的目的:

调查血液图参数对非ST段升高心肌梗塞 (非STEMI) 接受PCI的患者中CIN发展的预测作用.
确定特定的血液学标记,可以帮助早期CIN风险分层.

主要方法:

对387名被诊断患有非STEMI的患者进行了回顾性分析,这些患者在2017年至2020年期间接受了PCI.
采用多变量逻辑回归分析来确定CIN发展的独立风险因素.
评估包括MPV和NLr在内的血图参数,以及传统的风险因素,如年龄,糖尿病和心力衰竭.

主要成果:

晚年,糖尿病,充血性心力衰竭,对比度体积,MPV和NLr被确定为CIN的独立风险因素.
MPV和NLr与CIN发展有显著的关联 (分别为p=0.02和p=0.001).
对于NLr (5.5) 和MPV (9.05) 的特定截止值,在预测CIN.中显示出显著的灵敏度和特异性.

结论:

常规的血液学参数,特别是MPV和NLr,在接受PCI的非STEMI患者中是CIN的有价值预测指标.
这些标记物可以加强CIN风险评估,当与传统的风险因素一起使用时.
MPV和NLr是改善CIN预测和患者管理的有希望的,易于使用的工具.

关键词:

一百零五年 - - 一百零五年对比诱导的脏病引起的脏病.血小板的平均体积是多少中性粒细胞淋巴细胞比率.

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