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Updated: Jun 26, 2026

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
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Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

Published on: September 5, 2019

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scTopoGAN:单细胞数据的无监督的多元组对齐

Akash Singh1, Kirti Biharie1,2,3, Marcel J T Reinders1,2,3

  • 1Delft Bioinformatics Lab, Delft University of Technology, 2628 XE Delft, The Netherlands.

Bioinformatics advances
|December 11, 2023
PubMed
概括

scTopoGAN允许单细胞多原子数据集的无监督对齐,没有重叠的细胞或特征. 该方法使用拓自编码器和生成对抗网络来实现强大的数据集成和增强的多omic解释.

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Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...