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对比增强超声波提高了甲状腺结节的诊断准确度:一个前性的多中心研究

Jianming Li¹, Jianping Dou¹, Huarong Li²

¹Department of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital, Beijing 100853, China.

Journal of the Endocrine Society

|December 11, 2023

概括

将常规超声波 (US) 与对比度增强US (CEUS) 结合起来,可显著提高诊断甲状腺结节的准确性. 这种增强的方法有助于更好地区分恶性和良性结节.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
在瘤学瘤学.

背景情况:

甲状腺结节很常见,准确的诊断对于适当的管理至关重要.
传统的超声波 (US) 是主要的诊断工具,但其在区分良性和恶性结节的准确性可能是有限的.

研究的目的:

评估常规US与对比增强US (CEUS) 结合用于甲状腺结节的诊断性能改善.

主要方法:

一项涉及515名323名恶性和192名良性甲状腺结节的参与者的研究在中国的8个中心进行.
开发了US和US+CEUS的诊断标准,并使用多变量逻辑回归和接收器操作特征 (ROC) 分析比较性能.
美国放射学学院 (ACR) 甲状腺成像报告和数据系统 (TIRADS) 用于美国的评估.

主要成果:

研究人员确定的标准显示,与ACR TIRADS (0.83;P <.001) 相比,CEUS TIRADS (0.87) 的曲线下面面积 (AUC) 得到改善.
诊断回归模型显示,US + CEUS (0.84) 与单独使用US (0.76;P = .001) 的AUC显著更高.
包含CEUS的模型显示出优异的性能,在验证队列中得到证实.

结论:

将传统的US与CEUS结合起来,可以提高甲状腺结节的诊断准确度.
这种综合方法提供了一种更可靠的方法来区分良性和恶性甲状腺病变.

关键词:

与对比度增强的超声波.甲状腺癌是甲状腺癌.甲状腺结节甲状腺结节超声波超声波是指超声波的使用.

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