茶饮和减轻生物衰老:从两个队列研究的纵向分析
Yi Xiang1, Hao Xu2, Hongxiang Chen1
1West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
The Lancet regional health. Western Pacific
|December 11, 2023
概括
经常喝茶与缓慢的生物衰老有关. 适度摄入,每天大约3杯,显示出最显著的抗衰老作用,可能有助于制定健康的衰老策略.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 生物衰老可以受到生活方式的影响,但对茶的影响的人类研究有限.
- 了解茶饮等生活方式因素是预防与年龄有关的疾病和延长健康寿命的关键.
- 有限的基于人口的证据存在关于茶饮食及其对人类生物衰老过程的影响.
研究的目的:
- 调查茶饮与生物衰老加速之间的关联.
- 为了确定持续或不断变化的茶饮习惯是否会影响生物衰老的速度.
- 探索茶叶摄入量与生物衰老标志物之间的剂量反应关系.
主要方法:
- 利用了来自中国多民族队列 (CMEC) 和英国生物银行 (UKB) 研究的数据.
- 使用Klemera Doubal方法 (KDM) 计算生物衰老加速,并使用临床和人体测量数据.
- 采用了变化对变化和前性暴露-反应分析来评估茶饮对生物衰老的影响.
主要成果:
- 持续饮用茶叶与两个队伍的减弱生物衰老加速有关.
- 从不喝茶过渡到喝茶显示生物衰老加速的减少.
- 适度饮用茶 (大约) 每天3杯/6-8克叶子) 显示出最显著的抗衰老益处.
结论:
- 茶的消费,特别是适度和持续的饮用,与生物衰老的减缓有关.
- 研究结果支持茶在以营养为导向的抗衰老干预措施中的作用.
- 结果可以为健康老龄化政策和关于茶叶消费的公共卫生建议提供信息.
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