补充来自BB091109的后生菌改善了健康女性的炎症状况和内分泌功能:一种随机,双盲,安慰剂控制,并行组研究
Diana Elena Motei1, Beyda Beteri1, Piril Hepsomali2
1School of Life and Health Sciences, University of Roehampton, London, United Kingdom.
补充Bifidobacterium breve后生物提取物改善了内分泌功能,并减少了40岁以上女性的炎症. 这项研究强调了对荷尔蒙平衡和炎症标志物的潜在益处.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 内分泌学 在内分泌学.
背景情况:
- 来自有益细菌 (如Bifidobacterium breve) 的后生物质越来越多地被认为具有促进健康的特性.
- 保持荷尔蒙平衡和控制炎症对妇女的健康至关重要,特别是在中年.
研究的目的:
- 评估Bifidobacterium breve BB091109后生菌提取物对40-55岁女性炎症细胞因子和内分泌标志物的影响.
- 评估补充剂停止后这些影响的持续时间.
主要方法:
- 一项为期12周的双盲,安慰剂控制,随机化试验,涉及30名健康女性 (年龄在40-55岁).
- 参与者每天接受500mg的B. breve后生物提取物或安慰剂.
- 血液和唾液样本在基线,第4周,第12周和第16周分析了C反应蛋白 (CRP),IL-6,IL-10,TNF-α,IFN-γ,DHEA,雌激醇,雌醇,孕激素,皮质醇和人类生长激素.
主要成果:
- 在C-反应蛋白 (CRP) 和IL-6 (IL-6) 水平上观察到显著的改善.
- 补充剂显著影响了脱氨 (DHEA),雌醇和雌醇水平.
- 这些炎症和内分泌标志物的积极变化持续了补充后4周.
结论:
- 用B. breve后生物提取物补充饮食有效地提高40岁以上女性内分泌功能.
- 后生菌提取物对炎症标志物具有保护作用,这表明它在减轻炎症方面发挥了作用.
- 这些发现支持B. breve后生菌在促进荷尔蒙平衡和减少中年妇女炎症方面的潜力.
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