阿司匹林在接受横支气管肺冷藏活检的患者中是安全的
Lilach Israeli-Shani1,2, Avishag Tzur Dotan2, Elad Guber1,2
1Department of Pulmonology, Meir Medical Center, Kfar Saba, Israel.
Heliyon
|December 11, 2023
概括
这项研究发现,阿司匹林对于跨支气管肺结核切除术 (TBLC) 是安全的,但同时使用克洛皮多格雷尔会增加出血风险. 结核血栓癌可以安全地使用阿司匹林,不包括服用克洛皮多格雷尔的患者.
科学领域:
- 肺部病理学 肺部病理学
- 干预性肺病学 干预性肺病学
- 麻醉学 麻醉学
背景情况:
- 阿司匹林被认为是安全的各种支气管检查程序.
- 在跨支气管肺冷活检 (TBLC) 期间使用阿司匹林缺乏安全数据.
研究的目的:
- 在TBLC期间评估与阿司匹林使用相关的出血风险.
主要方法:
- 对172名接受TBLC治疗的患者进行了回顾性队列研究.
- 根据所需的干预措施分类出血的严重程度 (轻度,中度,严重).
主要成果:
- 在阿司匹林使用者 (29.6%) 和对照者之间,中度至重度出血没有显著差异.
- 同时使用克洛皮多格勒和阿司匹林显著增加出血风险 (OR=9.8,p=0.013).
- 没有观察到肺胸部,住院或死亡风险的增加.
结论:
- 对于服用阿司匹林的患者来说,TBLC似乎是安全的,除了那些同时服用克洛皮多格雷尔的患者.
- 同时使用克洛皮多格雷尔是TBLC期间出血的重要危险因素.
- 建议进行进一步的研究来证实这些发现.
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