微生物学和血液学方面的犬类 pyometra 和相关的风险因素
Madhav Paudel1, Sujan Kafle1, Tulsi Ram Gompo2
1Faculty of Animal Science, Veterinary Science and Fisheries, Agriculture and Forestry University, Chitwan, Rampur, Nepal.
Heliyon
|December 11, 2023
概括
狗皮奥美特与年龄,激素使用和白细胞数量的改变有关. 大肠杆菌和 Pseudomonas 是常见的,Imipenem,Amikacin 和 Gentamicin 显示出对这些细菌的最大有效性.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 狗的繁殖 狗的繁殖
- 细菌学 细菌学是一门学科.
背景情况:
- 狗的皮奥美特拉,或囊性子宫内膜异位增生综合体,是雌性狗中普遍存在的生殖障碍.
- 了解风险因素和致病因子对于有效的治疗和疾病管理至关重要.
研究的目的:
- 为了识别与犬类pyometra相关的风险因素.
- 分析受影响狗的血液学变异.
- 确定常见的细菌分离物及其抗生素敏感性模式.
主要方法:
- 从45只感染pyometra的母狗中培养样本以分离细菌.
- 抗生素测试用于评估细菌分离物对各种抗生素的敏感性.
- 统计分析以确定显著的风险因素 (如年龄,激素的使用) 和临床症状.
主要成果:
- 年龄,美德乙酸的使用和白细胞变化是显著的危险因素 (P<0.05).
- 封闭的宫肌测量显示出比开放的宫肌测量更严重的临床症状.
- 这就是E.I.E.的意思. 大肠杆菌 (35.55%) 和伪虫种类. (26.66%) 是最常见的分离物; 伊米佩内姆,阿米卡辛和热塔米辛是最有效的,而安皮西林和红素显示出高耐药性.
- 常见的是常态细胞,常态染色体,非再生性贫血;观察到升高的AST,ALT,ALP,BUN和肌素.
结论:
- 早期诊断和抗菌素易感性测试对于有效治疗犬类pyometra至关重要.
- 在26个分离物体中观察到多种药物耐药性,突出显示了由于滥用而导致的抗菌素耐药性的威胁.
- 有效的抗生素选择包括Imipenem,Amikacin和Gentamicin用于常见的pyometra病原体.
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