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关于gliclazide-carplex固体分散剂和用直接可压缩的共同加工辅助剂制备的片剂的物理化学报告

Subrata Paul1, Kaniz Fatema Asha1, Israt Zerin Alam1

  • 1Department of Pharmacy, Faculty of Science, University of Rajshahi, Bangladesh.

Heliyon
|December 11, 2023
PubMed
概括

这项研究开发了使用固体分散剂 (SD) 和共同加工的辅助剂的改进的gliclazide片剂配方,与商业产品相比,大大提高了药物释放率.

关键词:
卡尔普莱克斯是一个卡尔普莱克斯.共同加工的辅助剂 辅助剂格利克拉化物是什么在体外溶解过程中溶解.固体分散的分散方式药片 药片 药片 药片

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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