数字乳腺图解合成能够减少老年妇女的额外检查的能力
Maha Gharaibeh1, Ahmad Abu Alfwares2, Eyhab Elobeid1,3
1Department of Diagnostic and Interventional Radiology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Frontiers in medicine
|December 11, 2023
概括
数字乳房图解 (DBT) 显示,在老年妇女中,特别是乳房密集的妇女中,化检测的灵敏度有所提高. 然而,DBT并没有显著减少与2D乳房影像和超声波相比,对额外的医学检查的需求.
科学领域:
- 放射学和成像科学 放射学和成像科学
- 瘤学和癌症研究研究.
- 老年医学 老年医学
背景情况:
- 在老年妇女中评估数字乳腺图解合成 (DBT) 的诊断性能对于优化乳腺癌查协议至关重要.
- 了解乳腺密度如何影响DBT的准确性,与传统的2D乳房造影和超声波相比,对于临床决策至关重要.
研究的目的:
- 评估不同乳房密度的老年女性DBT的诊断性能.
- 为了比较DBT的癌症检测效率与二维乳房影像和超声波.
- 预测使用DBT的老年妇女不必要的额外检查的潜在减少.
主要方法:
- 一组224名老年妇女接受了二维乳房影像和DBT检查.
- 对每个成像模式计算了灵敏度,特异性,正预测值 (PPV),负预测值 (NPV) 和曲线下的面积 (AUC).
- 用二进制逻辑回归来预测DBT对减少对补充成像的需求的影响.
主要成果:
- 与非密集乳房相比,DBT在密集乳房中检测病变的灵敏度和NPV更高,但AUC更低.
- 经过DBT检测,在密集乳房和非密集乳房中检测化时,敏感度和NPV显著提高.
- 对于病变检测,二维乳房扫描显示出最高的整体灵敏度,其次是DBT,然后是超声波. 与2D造乳镜相比,DBT显示出更高的化检测灵敏度.
结论:
- 数字乳腺图解合成 (DBT) 提供了更好的化检测在老年妇女,特别是那些有密集的乳房.
- 尽管取得了进展,但DBT并没有显著减少这一群体进一步医疗检查的需要.
- 进一步的研究可能是有必要的,以探索DBT在老年妇女中综合性乳腺癌查的其他方式的作用.
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