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亚洲的NAFLD和NAFLD相关的HCC:负担和监测

Jia H Koh¹, Meng Wang¹, Hiroyuki Suzuki²

¹Department of Medicine, National University Hospital, Singapore, Singapore.

Journal of clinical and experimental hepatology

|December 11, 2023

概括

非酒精性脂肪性肝病 (NAFLD) 是亚洲慢性肝病的日益严重的原因,增加肝细胞癌 (HCC) 风险. 对于没有肝硬化的NAFLD患者,需要新的监测策略.

科学领域:

肝病学肝病学是一种肝病学.
在瘤学瘤学.
公共卫生公共卫生

背景情况:

非酒精性脂肪性肝病 (NAFLD) 是亚洲慢性肝病 (CLD) 的主要原因.
NAFLD的发病率正在上升,预计NAFLD相关的肝癌 (肝细胞癌,HCC) 的增加.
很大一部分NAFLD-HCC病例发生在没有肝硬化的患者中.

研究的目的:

审查亚洲NAFLD和HC的发展趋势.
讨论对NAFLD患者HCC监测的影响.
突出需要在没有肝硬化的NAFLD患者中改进HCC风险分层.

主要方法:

关于亚洲NAFLD和HCC趋势的文献综述.
对当前HCC查指南的分析.
讨论监控的成像方式.

主要成果:

在亚洲,NAFLD是导致CLD和HCC的主要驱动因素.
在没有肝硬化的情况下,HCC可以在NAFLD患者中发展.
目前的指导方针侧重于肝硬化对HCC查,需要针对非肝硬化NAFLD患者制定新的策略.

结论:

改善HCC风险分层对于没有肝硬化的NAFLD患者至关重要.
需要加强监测策略,以应对亚洲日益增加的NAFLD-HCC负担.
对非肉性NAFLD风险分层模型的进一步研究是有必要的.

关键词:

亚洲亚洲亚洲亚洲在HCC中,HCC是HCC.这是NAFLD.肝细胞癌是肝细胞癌.非酒精性脂肪性肝病是非酒精性脂肪性肝病.

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