滥用1,4-butanediol的后果:一个审查
VYu Skryabin1, YuB Shevtsova2, E A Novoselova3
1Skryabin, MD, PhD, associate professor of addiction psychiatry department, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russian Federation.
1,4-Butanediol (1,4-BD) 被滥用以产生高兴效应,并且具有显著的精神活性特性. 本综述强调了它的成潜力和严重的戒断症状,强调了滥用1,4-BD的风险.
科学领域:
- 神经科学是一个神经科学.
- 临床药理学 临床药理学
- 毒理学 毒理学 毒理学
背景情况:
- -酸 (GHB),1,4-butanediol (1,4-BD) 和-butyrolactone (GBL) 是中枢抑郁药,非法用于娱乐用途.
- 这些物质因其高兴和放松作用而被滥用,这引起了公众健康的担忧.
研究的目的:
- 审查有关1,4-butanediol (1,4-BD) 滥用的现有文献.
- 描述1,4-BD中毒,成和妄想的临床表现.
主要方法:
- 关于滥用1,4-butanediol (1,4-BD) 的研究的文献综述.
- 对有关中毒,成和戒断综合征的临床数据的分析.
主要成果:
- 1,4-Butanediol (1,4-BD) 与GHB分开表现出明显的精神活性作用.
- 有证据表明,与使用1,4-BD相关的成潜力很高.
- 戒掉1,4-BD可以导致严重和潜在的危险症状.
结论:
- 1,4-butanediol (1,4-BD) 是一种滥用物质,具有重大风险.
- 临床医生应该意识到1,4-BD滥用,成和严重戒断的可能性.
- 需要进一步的研究,才能充分了解1,4-BD滥用的神经生物学机制和长期后果.
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