性差异在多发性硬化症,炎症性肠道疾病和类风湿性关节炎中明显增加焦虑症状
Jerlin Joyees1, Ruth Ann Marrie2,3, Charles N Bernstein2,4
1College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Frontiers in psychiatry
|December 11, 2023
概括
患有免疫媒介性炎症性疾病 (IMID) 的女性报告的焦虑症状比男性更多. 较低的收入与IMID男性的焦虑有关,突出了疾病管理中的性别特异性因素.
科学领域:
- 医学研究 医学研究
- 精神病学是一个精神病学.
- 免疫学 免疫学 免疫学
背景情况:
- 免疫媒介性炎症性疾病 (IMID),包括多发性硬化症 (MS),炎症性肠病 (IBD) 和类风湿性关节炎 (RA),经常与增加的焦虑症状有关.
- 焦虑会加剧疾病负担,并损害IMID患者的功能.
- 了解焦虑患病率和促成因素的性别差异对于有效的诊断和管理至关重要.
研究的目的:
- 调查IMID患者中高焦虑症状的发生频率的性别差异.
- 为了确定与焦虑症状相关的因素,这些焦虑症状可能在IMID的男性和女性之间有所不同.
主要方法:
- 一组656名患有IMID (MS,IBD或RA) 的参与者完成了验证的焦虑评估 (HADS,GAD-7).
- 后勤回归分析被用来比较性别之间的高焦虑症状的流行率和特定焦虑项目的认可.
- 与焦虑相关的因素被检查为基于性别的变化.
主要成果:
- 患有IMID的女性比男性更有可能出现高焦虑症状 (aOR 2.05).
- 年龄较小,抑郁症状较高,收入较高与整体IMID队列中的焦虑有关.
- 较低的收入是IMID (aOR 4.8) 的男性焦虑的一个重要因素,但不是女性.
- 患有IMID的男性报告不安的几率更高 (OR 1.8).
结论:
- 在IMID患者中与高焦虑症状相关的因素中存在性别差异.
- 临床医生应该意识到这些特定于性别的关联,特别是IMID男性的低收入和焦虑之间的联系,以改善患者监测和护理.
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