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一种线粒体质量控制机制可以逆转由Mycobacterium tuberculosis引起的菌体成熟停止

Surbhi Verma, Mrinmoy Das, Raman D Sharma

    bioRxiv : the preprint server for biology
    |December 11, 2023
    PubMed
    概括

    削弱p62蛋白质会破坏线粒体质量控制,导致Mycobacterium tuberculosis对溶酶体的向性增强. 这种意想不到的交叉声调逆转了细胞成熟的停止,为结核病治疗提供了新的途径.

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