SLCO1B1 功能变异和来自非洲的近期血统祖先的人群中的他类药物诱导肌肉病:基于人口的现实世界研究

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Updated: Jul 8, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

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Sook Wah Yee, Tanushree Haldar, Mark Kvale

    medRxiv : the preprint server for health sciences
    |December 11, 2023
    PubMed
    概括

    某些SLCO1B1基因变异增加了黑人群体的他胺肌病风险,需要纳入药物遗传学测试. 这项研究强调了临床指南中需要多样化的遗传数据,以防止与他类药物相关的毒性.

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