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Updated: Jul 8, 2025

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使用小鼠模型测试SIPA1L2作为CMT1A的修饰剂

George C Murray1,2, Timothy J Hines1, Abigail L D Tadenev1

  • 1The Jackson Laboratory, Bar Harbor, ME 04609.

bioRxiv : the preprint server for biology
|December 11, 2023
PubMed
概括

研究人员研究了信号诱导的扩散相关的1像2 (SIPA1L2) 作为Charcot-Marie-Tooth 1A (CMT1A) 神经病变的修饰剂. 虽然基因相互作用得到证实,但SIPA1L2删除对CMT1A症状的整体影响很小.

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