与健康儿童相比,患有发烧性的儿童的QT间隔变化
Noor Mohammad Noori1, Ali Khajeh1, Alireza Teimouri1
1Children and Adolescent Health Research Center, Research Institute of Cellular and Molecular Science in Infectious Diseases, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.
Basic and clinical neuroscience
|December 11, 2023
概括
儿童发烧性 (FC) 显著改变了QT间隔测量,特别是纠正的QT (QTc) 和分散的QT (QTcd). 这些变化凸显了发烧性发作的潜在心脏影响.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 临床电生理学 临床电生理学
背景情况:
- 发烧性 (FS) 是一种常见的儿童疾病,通常与温度升高有关.
- 作为心脏再极化度量的QT间隔,可以受到各种生理状态的影响,包括发烧性疾病.
研究的目的:
- 研究和比较患有发烧 (FC) 的儿童的QT间隔参数与健康对照组.
- 为了确定与FC相关的特定心电图 (ECG) 变化.
主要方法:
- 一项涉及180名儿童的病例控制研究,均分为FC和对照组.
- 儿童心脏病专家对QT间隔参数进行了心电图测量并进行了解释.
- 数据分析使用了SPSS软件,显著程度为P<0.05.
主要成果:
- 与对照人群相比,患有FC的儿童在心率 (HR),aVL中的R,V3中的S,左心室质量 (LVM),QTd,QTc和QTcd中表现出显著的差异.
- 在患有FC的儿童中,QTc (P<0.001) 和QTcd (P<0.001) 的异常明显更频繁.
- 虽然LVM在患有FC的24个月以上儿童中显著高 (P<0.001),但其他QT参数在FC组内没有显示出与年龄相关的显著变化.
结论:
- 纠正的QT (QTc),分散的QT (QTd) 和纠正分散的QT (QTcd) 在患有发烧的儿童中显著改变.
- 这些QT间隔变化在FC患者中在研究中的不同年龄组中是一致的.
- 这些发现表明发烧和心脏再极化异常之间存在潜在的联系.
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