用毒素成功治疗COVID-19后的神经性失调症
Riccardo Canta1,2, Lucilla Vestito1,2, Paola Castellini3,4
1Department of Neuroscience (DINOGMI), University of Genova, Genova, Italy.
European journal of case reports in internal medicine
|December 11, 2023
概括
这项研究提出了一种新的治疗方法,用于COVID-19后的吞障碍,这是由SARS-CoV-2病毒引起的吞困难. 一次成功的干预涉及A型肉毒素注射,为患有这种具有挑战性的疾病的患者提供了希望.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 缺食症是COVID-19后患者的潜在并发症,与SARS-CoV-2的神经效应有关.
- 口腔喉乱会影响住院COVID-19患者的很大一部分,有各种潜在的潜在原因.
- 在严重病例中,传统疗法可能会显示出有限的改善,因此需要使用替代治疗策略.
研究的目的:
- 报告首次成功治疗COVID-19相关的口腔喉功能障碍,使用甲型玻尿素毒素A型.
- 调查电生理学评估在诊断和管理COVID-19后食障碍方面的潜力.
- 突出毒素A型注射作为改善吞功能的可行的治疗选择.
主要方法:
- 一名患有严重COVID-19相关的口腔喉乱症的患者的病例报告,需要肠道养.
- 纤维内镜证实了消化不良;对喉肌进行了电生理学评估.
- 在对传统疗法的有限反应后,单侧喉注射甲型玻尿素毒素.
主要成果:
- 患者在A型肉毒素注射后的吞功能显著改善.
- 治疗使患者能够恢复口服养,表明成功的结果.
- 电生理学评估揭示了特定的肌肉功能障碍,指导了治疗决定.
结论:
- 通过神经路径,SARS-CoV-2可以引起食症,影响喉协调.
- 电生理学作为一个有价值的诊断和监测工具用于口腔喉乱.
- 毒素A型注射是一种有效的治疗COVID-19后食障碍,恢复口服摄入.
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