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Updated: Jul 8, 2025

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
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A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

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通过蛋白质-蛋白质相互作用分析识别可用药物的枢纽基因和与子宫癌相关的关键途径:一个in silico研究

Azizeh Asadzadeh1, Nafiseh Ghorbani2, Katayoun Dastan2

  • 1Department of Biology, Faculty of Science, Nour Danesh Institute of Higher Education, Meymeh, Isfahan, Iran.

International journal of reproductive biomedicine
|December 11, 2023
PubMed
概括

这项研究使用生物信息学分析确定了宫癌 (CC) 的关键基因和潜在药物标. 这些发现为CC患者提供了新的治疗策略,等待进一步的实验验证.

关键词:
DEGs. 这是一个很好的方法.基因表达 基因表达 基因表达枢纽基因 枢纽基因 枢纽基因宫癌是发生在宫癌的原因之一.蛋白质相互作用 蛋白质相互作用

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Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres

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相关概念视频

Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
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Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
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Interactions Between Signaling Pathways01:19

Interactions Between Signaling Pathways

Signaling cascades usually lack linearity. Multiple pathways interact and regulate one another, allowing cells to integrate and respond to diverse environmental stimuli.
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
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