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Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
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为生物医学应用而设计的基于环氧的超分子水凝.

Yuqi Zhao1, Zhi Zheng1, Cui-Yun Yu1

  • 1Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study & School of Pharmaceutical Science, Hengyang Medical School, University of South China, 28 W Changsheng Road, Hengyang 421001, Hunan, China. zhengzhi@usc.edu.cn.

Journal of materials chemistry. B
|December 11, 2023
PubMed
概括
此摘要是机器生成的。

基于环氧的超分子水凝提供了多功能药物输送解决方案. 本综述详细介绍了它们的设计,特性和生物医学应用,强调了临床翻译的未来前景.

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科学领域:

  • 材料科学 材料科学 材料科学
  • 聚合物化学 聚合物化学
  • 生物医学工程 生物医学工程

背景情况:

  • 基于环氧 (CD) 的超分子水凝是先进的聚合物网络.
  • 它们通过交叉连接迅速形成可逆的3D多孔结构.
  • 这些水凝对药物输送应用具有重大前景.

研究的目的:

  • 提供基于CD的超分子水凝的全面概述.
  • 详细介绍它们的结构,机械性能调制和药物输送能力.
  • 从交叉链接的角度探索它们在生物医学领域的应用.

主要方法:

  • 对基于CD的超分子水凝的现有文献进行系统审查.
  • 分析交叉连接策略及其对水凝性质的影响.
  • 药物加载,释放机制和生物医学应用的评估.

主要成果:

  • 基于CD的超分子凝设计和机械性能调节的详细描述.
  • 探索各种药物加载和释放模式.
  • 在瘤学,伤口带,骨修复和心肌组织工程中的应用概述.

结论:

  • 基于CD的超分子水凝为生物医学应用提供了一个有前途的平台.
  • 对其挑战和前景的进一步研究可以加速临床翻译.
  • 本综述为开发先进的基于CD的水凝提供了见解.