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在过度活动的膀中对骨神经和骨神经调节的反应:有任何相关性吗?

Mathieu Fourel¹, Samy Hafez², Nassima Ramdane³

¹Department of Urology, Lille Academic Hospital, University of Lille, Lille, France.

Neurourology and urodynamics

|December 11, 2023

概括

对穿皮神经刺激 (TTNS) 的反应不能预测神经神经调制 (SNM) 对于过度活跃的膀 (OAB) 的成功. 这些神经调节疗法在OAB治疗决策中应该独立考虑.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
神经调节是一种神经调节.
过度活跃的膀治疗

背景情况:

过度活跃的膀 (OAB) 显著影响生活质量.
穿皮神经刺激 (TTNS) 和十字神经调制 (SNM) 是用于OAB的神经调制疗法.
基于TTNS结果预测SNM反应可以优化治疗选择.

研究的目的:

评估患者对TTNS的反应和随后对OAB治疗SNM的反应之间的相关性.
为了确定TTNS疗效是否预测SNM在OAB患者队列中的成功.

主要方法:

一项回顾性研究包括92名OAB患者,他们接受了TTNS,随后进行了两阶段SNM.
成功被定义为烦性尿路症状的改善≥50%.
后勤回归分析评估了TTNS和SNM反应之间的关系,对年龄,性别和神经疾病进行控制.

主要成果:

TTNS的成功率为23.9% (22/92),而SNM测试阶段的成功率为71.7% (66/92).
在总人口中,TTNS反应和SNM反应之间没有发现统计学意义上的相关性 (p=0.51).
在对年龄子组进行控制时,这种缺乏相关性仍然存在.

结论:

对TTNS的反应不是OAB患者SNM反应的可靠预测指标.
TTNS和SNM应该被视为不同的治疗选择.
对OAB管理的临床决策应独立考虑这些疗法.

关键词:

过度活动的膀预测性预测性预测性关系关系关系关系关系关系关系.节骨神经调节神经神经调节通过皮肤进行神经刺激.

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