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Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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NADPH氧化酶2-衍生反应性氧物种促进CD8+T细胞效应器功能

Jing Chen1, Chao Liu1, Anna V Chernatynskaya1

  • 1Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL.

Journal of immunology (Baltimore, Md. : 1950)
|December 11, 2023
PubMed
概括

NADPH氧化酶2 (NOX2) 对于CD8+ T细胞效应器功能至关重要. 抑制NOX2会损害T-bet表达,细胞因子产生和 lysis,揭示其在T细胞激活中的非冗余作用.

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