Gallbladder perforation in acute acalculous vs. calculous cholecystitis:一项回顾性比较队列研究,其中包括10年的单一中心经验
Kyong Joo Lee1, Se Woo Park1, Da Hae Park1
1Department of Internal Medicine.
International journal of surgery (London, England)
|December 11, 2023
概括
与胆结石相比,性胆囊炎显著增加了胆囊穿孔 (GBP) 的风险. 早期胆囊切除术对于减少GBP并发症和死亡率至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 外科手术的结果
- 胆囊疾病 胆囊疾病
背景情况:
- 胆结石是急性胆囊炎的已知危险因素.
- 胆囊穿孔 (GBP) 中胆结石的作用尚未得到充分证实.
- 这项研究调查了胆结石作为英的风险因素.
研究的目的:
- 为了确定胆结石对胆囊穿孔 (GBP) 的发展的影响.
- 为了比较英风险,计算型胆囊炎 (AC) 和计算型胆囊炎 (CC) 之间的风险.
主要方法:
- 对4497名因急性胆囊炎接受胆囊切除术的患者进行了回顾性队列研究.
- 主要终点:胆结石作为英的风险因素.
- 二级终点:胆囊切除术的临床特征,风险因素,结果和时间.
主要成果:
- 在AC (5.6%) 的GBP发病率高于CC (1.0%).
- 在AC患者中,GBP的风险增加了5倍.
- 延迟胆囊切除术增加了GBP发病率 (2.0%与0.9%相比).
结论:
- 结石性胆囊炎是胆囊穿孔的重要危险因素.
- 早期胆囊切除术减少了与英相关的发病率和死亡率.
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