在外国出生的加拿大人中结核感染的流行:一项建模研究
Aria Ed Jordan1, Ntwali Placide Nsengiyumva1, Rein M G J Houben1
1Department of Epidemiology, Biostatistics, and Occupational Health (Jordan), McGill University; McGill International Tuberculosis Centre (Jordan, Nsengiyumva, Ahmad Khan, Campbell, Schwartzman); Respiratory Epidemiology and Clinical Research Unit (Nsengiyumva, Ahmad Khan, Campbell, Schwartzman), Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montréal, Que.; Department of Infectious Disease Epidemiology and Tuberculosis Centre (Houben), Tuberculosis Modelling Group, London School of Hygiene and Tropical Medicine, London, UK; School of Health and Related Research (Dodd), University of Sheffield, Sheffield, UK; Victorian Tuberculosis Program (Dale, Denholm), Melbourne Health, at the Peter Doherty Institute for Infection and Immunity; School of Public Health and Preventive Medicine (Trauer), Monash University; Department of Infectious Diseases (Denholm), University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia; British Columbia Centre for Disease Control (Johnston); Department of Medicine (Johnston), University of British Columbia, Vancouver, BC; Departments of Medicine and of Global and Public Health (Campbell), McGill University, Montréal, Que.
大约四分之一的出生在国外的加拿大人患有结核病感染,大多数感染是在抵达之前获得的. 最近的几例感染表明,目前的查政策可能对预防结核病有效.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 结核病感染的流行率对于在加拿大设计预防策略至关重要.
- 此前,有关外国出生的加拿大人肺结核感染患病率的数据并不存在.
研究的目的:
- 估计加拿大外国出生的居民中结核感染的流行率.
- 根据年龄和迁移年份分析结核病感染的流行率.
主要方法:
- 使用模型估计年度感染风险的特定国家和特定日历年趋势.
- 与2001年至2021年加拿大人口普查数据结合的国家特异性流行率估计.
- 外国出生加拿大居民的计算总体患病率.
主要成果:
- 从2001年到2021年,在外国出生的加拿大人中,结核病感染的总体患病率为22-25%.
- 患病率随着移民年龄和原籍国结核病发病率的增加而增加.
- 2021年,北克的患病率最低 (19%),阿尔伯塔和不列颠哥伦比亚省的患病率最高 (24%).
结论:
- 大约四分之一的外籍加拿大人携带结核病感染.
- 在人口普查之前的两年内,很少有人感染.
- 这些发现可以为加拿大未来的结核病感染查政策提供信息.
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