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在HER2阳性乳腺癌中,SIRT6促进转移和复发

Cristina Andreani1,2, Caterina Bartolacci3,4, Giuseppe Persico5

  • 1Department of Biosciences and Veterinary Medicine, University of Camerino, 62032, Camerino, Italy. Cristina.Andreani@unicam.it.

Scientific reports
|December 11, 2023
PubMed
概括

高素6 (SIRT6) 水平会促进HER2阳性侵袭性乳腺癌,增加转移并降低存活率. SIRT6抑制T盒转录因子3 (TBX3),这是一个更好的预后标志.

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