在长平区新生中结核查的特点,北京,中国
Xiaolong Cao1,2, Zexuan Song1, Wencong He1
1Chinese Center for Disease Control and Prevention, National Tuberculosis Reference Laboratory, No. 155 Chang Bai Road, Changping District, Beijing, 102206, People's Republic of China.
BMC infectious diseases
|December 11, 2023
概括
在北京的新生中发现了高潜伏结核病感染率 (LTBI). 结核病预防疗法 (TPT) 的普及率很低,特别是在职业学院,这凸显了需要在学校改进TPT的实施.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 在学校进行结核病 (TB) 查对于降低患病率至关重要.
- 结核病预防疗法 (TPT) 防止潜伏结核病感染 (LTBI) 的进展.
- 在学生群体中对LTBI和TPT的研究有限.
研究的目的:
- 评估北京长平区新生中LTBI的流行情况.
- 调查影响LTBI率和TPT吸收的因素.
- 倡导在教育环境中加强TPT的实施.
主要方法:
- 这项前性研究涉及12所教育机构的19872名新生.
- 包括Kolmogorov-Smirnov测试在内的统计分析,以确定LTBI率和影响因素.
- 在中国对LTBI治疗的TPT应用和疗效的评估.
主要成果:
- 11.6%的学生患有LTBI;发现了18例活跃的结核病例.
- 在1045名LTBI个人中,只有312人选择了TPT.
- 与大学相比,职业学院的TPT率明显较低 (P < 0.001).
- 一个强阳性纯化蛋白衍生物 (PPD) 试验与不同年龄段的LTBI有显著的相关性 (P < 0.001).
结论:
- 在学生中高的LTBI率构成跨区域结核病传播的风险.
- 教育水平似乎影响了TPT的吸收.
- 改善TPT的实施对于学校的结核病控制至关重要.
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