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诺莫图谱用于预测腹腔镜下前切除直肠癌后的长期术后阴道

Fangliang Guo¹, Zhiwei Sun¹, Zongheng Wang¹

¹Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People's Republic of China.

World journal of surgical oncology

|December 12, 2023

概括

一个新的名图预测了腹腔镜下前切除直肠癌后的长期手术后阴道 (PPOI). 该工具有助于识别高风险患者,改善手术结果和患者护理.

科学领域:

结肠直肠手术结肠直肠手术
手术瘤学手术瘤学
医学中的预测分析.

背景情况:

长期的术后阴道 (PPOI) 是结直肠手术后的常见并发症,导致患者发病率增加和医疗费用增加.
目前缺乏对腹腔镜前下切除 (LAR) 患者PPOI风险的预测工具.
开发预测模型对于主动的患者管理至关重要.

研究的目的:

开发和验证用于预测腹腔镜前下切除 (LAR) 进行直肠癌的患者中PPOI的诺米克图.
确定与PPOI发展相关的关键临床和外科因素.
为患者早期风险分层提供一个工具.

主要方法:

对548名接受了腹腔镜LAR治疗直肠癌的患者进行了回顾性分析.
后勤回归分析以确定PPOI的独立预测因素.
使用启动重新抽样和性能指标 (AUC,校准曲线) 构建和内部验证Nomogram.

主要成果:

PPOI的发生率为13.1% (72/548名患者).
PPOI的独立预测因素包括晚年,低albuminemia,高手术困难,以及术后阿片类药物使用.
开发的诺米图表表现出良好的预测性能,AUC为0.738.

结论:

一种新型的诺米图有效地预测了腹腔镜LAR后的PPOI风险,用于直肠癌.
这种工具可以帮助外科医生识别高风险个体.
诺米图表促进了个性化的患者护理,并可能减少PPOI的发生率.

关键词:

低前切除的前部切除.这个名字叫做Nomogram.长时间的手术后阴.这是直肠癌.

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