基于医院的益生菌管理的实施策略,在一个阶梯集群随机试验设计中,用于预防医院获得的Clostridioides difficile感染
Lauren C Bresee1,2, Nicole Lamont3, Wrechelle Ocampo3
1Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
BMC health services research
|December 12, 2023
概括
实施有针对性的益生菌策略有效地改善了接受抗生素的老年人对抗生素的坚持,降低了医院获得的Clostridioides difficile感染风险. 这种多方面的方法提高了患者的护理和结果.
科学领域:
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 困难菌感染 (CDI) 对住院的老年人构成重大风险.
- 需要有效的预防策略,如益生菌,但面临实施挑战.
- 及时服用益生菌对于预防医院获得的CDI (HA-CDI) 是至关重要的.
研究的目的:
- 评估有效的益生菌实施策略,以预防老年人HA-CDI.
- 评估益生菌干预的实际有效性 (预防CDI-55+).
- 为了识别和克服及时管理益生菌的障碍.
主要方法:
- 在四家医院进行了一项阶梯集群随机对照试验.
- 该干预涉及一种益生菌 (Bio-K+®) 用于55岁以上接受全身抗菌药物治疗的患者.
- 一个多方面的战略包括电子决策支持,网站冠军和教育;重点小组确定了障碍.
主要成果:
- 一个全面的实施战略涉及340个教育课程和1800多名参与者.
- 专注小组导致了电子支持和护理教育的调整.
- 益生菌的坚持率在开始服用抗生素72小时内从66.7%到75.8%不等.
结论:
- 一种针对障碍的多面性方法成功改善了益生菌的坚持性.
- 关键组成部分包括电子决策支持,教育和适应性实施规划.
- 这一策略在现实世界医疗保健环境中证明了其有效性.
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