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Updated: Jul 8, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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费里替诺法基介导的铁致死促进了由高流动性组盒1 (HMGB1) 引起的甲基酸甲肝毒性

Chengbo Wang1, Maodong Leng1, Cong Ding1

  • 1Institute of Pediatric Medicine, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou, Henan, China.

Liver international : official journal of the International Association for the Study of the Liver
|December 12, 2023
PubMed
概括

甲索特雷克萨特 (MTX) 通过铁死 (ferroptosis) 引起肝损伤,这是一种涉及费里丁和HMGB1.1的过程. 抑制这些途径,特别是用糖酸,可以治疗MTX诱导的肝毒性.

关键词:
这就是HMGB1的特点.自自是自的过程.费里提诺代 (ferritinophagy) 是一种对铁素的消化.铁性化 (ferroptosis) 是一种甲基特雷克萨酸盐的使用方法

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