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Updated: Jul 8, 2025

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多原子集成揭示了神经元-细胞外囊泡协调在退化中的质反应

Adrian V Cioanca1,2, Yvette Wooff1,2, Riemke Aggio-Bruce1,2

  • 1Clear Vision Research Group, Eccles Institute of Neuroscience, John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Canberra, Australia.

Journal of extracellular vesicles
|December 12, 2023
PubMed
概括

神经元通过携带微RNA (miRNA) 的细胞外囊泡 (EV) 与质细胞进行通信. 这种EV介导的神经元到质信号调节炎症,并可能为神经退行性疾病提供治疗点.

关键词:
中枢神经系统中枢神经系统细胞外囊泡中的细胞外囊泡.格利亚 (Glia) 是一个.神经退行症的神经退行症视网膜 视网膜 视网膜 是一个组织交叉对话.

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Proteins and neurotransmitters in secretory vesicles can be released from a cell upon vesicle docking, priming, and fusion with the plasma membrane. Vesicles are docked and primed in preparation for the quick exocytosis of their contents in response to a stimulus. The fusion process is mainly carried out by a SNAP Receptor or SNARE complex, consisting of synaptobrevin, syntaxin-1, and SNAP-25.
In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
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